The house is resided in a closed quarter near the airport and the bus terminal (Terminal Terrestre) and is a perfect starting point to explore Ecuador, by trips to the Andes (Quito, Cuenca, Riobamba) and coast (Routa del Sol). Also flights to theGalapagos Islands starts in Guayaquil. You can lodge your baggage there if you need. My locally partner (speaking Spanish, English, German just a little) can assist you bei questions/enterprises, when I personally will be outside.
Have a nice trip!